The EU Strategy towards the Eradication of Trafficking in Human Beings 2012–2016 recognises the importance of comprehensive child-sensitive protection systems, for which a robust guardianship system serves as a touchstone. Effective guardianship systems are key to preventing abuse, neglect and exploitation. Yet the roles, qualifications and competences of guardians vary from one Member State to another. This handbook, a joint publication of the European Commission and the European Union Agency for Fundamental Rights, is designed to help standardise guardianship practice, ensuring also that it is better equipped to deal with the specific needs of child victims of trafficking. It provides guidance and recommendations to EU Member States on strengthening their guardianship systems, setting forth the core principles, fundamental design and management of such systems. By promoting a shared understanding of the main features of a guardianship system, it aims to improve conditions for children under guardianship and promote respect for their fundamental rights.